Book Microbiome Stool Tests in Leicester
We commonly use the two options below to assess the gut.
GI Effects
Genova’s stool profiles provide a more complete evaluation of gut health.
The combination of PCR, culture, and microscopic testing methods ensures that any relevant organisms are identified.
The health of the entire body is dependent on a healthy gut and gut microbiome. Gut microbes are co-dependent with one another and with their human host. The health of one affects the other. A sizeable volume of research associates a dysbiotic, or imbalanced, gut microbiome with multiple disease states both within and outside of the GI tract. The diverse metabolic activities of the microbiome ultimately impact the human host, and the activities of the human host ultimately affect the health of their microbiome.
Systemic diseases can be linked to the GI tract, and improving the health of your gut may improve your overall health.
Specialist stool testing provides information on inflammation and how well you digest and absorb your food. Stool testing can also uncover imbalances in yeast, parasites, and the healthy and unhealthy bacteria that live in the large intestine. This bacterial population is called your microbiome.
GI Effects Stool Profiles
The GI Effects Stool Profiles are a suite of advanced stool tests that provide immediate, actionable clinical information for the management of gastrointestinal health. Utilising cutting-edge technologies and biomarkers, these profiles offer valuable insight into digestive function, intestinal inflammation, and the intestinal microbiome.
The GI Effects Stool Profiles can reveal important information about the root cause of many common gastrointestinal symptoms and non-GI conditions, including:
Invivo - MetaXplore™ GI Plus
MetaXplore GI Plus is a comprehensive gastrointestinal and microbiome health test that offers deep insights into gut function, microbial balance, and the presence of pathogens. It assesses seven key GI health markers and uses advanced PCR technology to detect 13 bacterial pathogens and 5 protist parasites with high accuracy. The test also evaluates microbiome diversity and richness, essential indicators of gut health, and analyses microbial functional markers like SCFA production, bile acid metabolism, and inflammation. Results are compared against a reference group of 484 exceptionally healthy individuals for context.
An interactive Species Explorer allows detailed analysis of microbial species linked to health or disease. The test also examines how gut health influences six major health areas, including digestion, immunity, metabolism, brain-gut function, cardiovascular health, and inflammation. Users receive over 80 science-based insights with personalised diet, lifestyle, and supplement recommendations. An interactive digital report with built-in interpretation support makes it easy to understand and share results with healthcare providers.
Can identify over 28,000 microbial species, including:
- 2,953 fungal species
- ~240 archaeal species
- 425 protist species
- 410 oral species
MetaXploreTM GI Plus: Testing Method & Capabilities
- Metagenomics: Identifies microbes to the species level, Assessment of up to 28,000 different species.
- Metagenomics: Identifies microbes to the species level, Assessment of up to 28,000 different species.
- PCR: NATA-accredited pathogen detection, highly sensitive detection, 13 bacterial and 5 protist parasite targets.
- Metagenomics: Complete picture of the whole microbiome, Assessment of 20 different functional markers.
Biomarkers
- Diagnostic Gastrointestinal Markers: Calprotectin (intestinal inflammation), Faecal occult blood, Lactoferrin (inflammation), Pancreatic elastase (exocrine pancreas function), Secretory IgA (mucosal immunity), Zonulin (intestinal permeability)
- Investigative Marker: Faecal pH (gut environment and fermentation activity)
- Microbial Pathogen Detection (via PCR + metagenomics): Bacterial pathogens: E. coli pathotypes, Clostridioides difficile, Campylobacter spp., Salmonella spp., Yersinia enterocolitica, Vibrio spp., Aeromonas spp. Protist parasites: Giardia lamblia, Entamoeba histolytica, Cryptosporidium spp., Cyclospora cayetanensis, Dientamoeba fragilis (emerging pathogen).
- Microbiome Community Metrics: Taxonomic profiling of over 28,000 microbial species (bacteria, archaea, fungi, yeasts, protists), Microbial alpha diversity and richness, Relative abundance of key genera (e.g., Bifidobacterium, Faecalibacterium, Akkermansia, Ruminococcus)
- Microbial Functional & Metabolic Markers: Short-chain fatty acids: butyrate, acetate, propionate. Other metabolites: 3-indolepropionic acid (IPA), trimethylamine (TMA), hydrogen sulphide, branched‑chain amino acids (BCAA), and methane. Immune/growth modulators: hexa-acylated LPS (hexa-LPS), B. fragilis toxin, beta‑glucuronidase. Emerging markers: histamine, ammonia (via urease), GABA production/consumption, vitamin K synthesis, lactate, human DNA presence. Substrate consumption: mucin, oxalate.
- Fungal Profiling: Comprehensive analysis of fungal genera, including Candida and Saccharomyces.
- Parasite & Protist Profiling: Detection of Blastocystis subtypes 1–9 and other protists.
Book Urine Tests in Leicester
We commonly use the five options.
OATS Organic Acids Urine Test
The Organic Acids Test (OAT) offers a comprehensive metabolic snapshot of your overall health with 76 markers. Organic acids are produced during your body’s day-to-day metabolism. A number of these organic acids produced indicate deficiencies of critical vitamins or other imbalances in your body.
Some of the organic acids produced provide an accurate evaluation of intestinal yeast and bacteria or the presence of intestinal dysbiosis (imbalance of yeast or bacteria). Abnormally high levels of these microorganisms can cause or worsen behaviour disorders, hyperactivity, movement disorders, fatigue and immune function. Many people with chronic illnesses and neurological disorders often excrete several abnormal organic acids in their urine. The cause of these high levels could include oral antibiotic use, high sugar diets, immune deficiencies, acquired infections, as well as genetic factors.
Great Plains Organic Acids Test also includes markers for vitamin and mineral levels, oxidative stress, and neurotransmitter levels, and is the only OAT to include markers for oxalates, which are highly correlated with many chronic illnesses.
Great Plains Organic Acid testing is useful for
- Fatigue, including chronic fatigue and fibromyalgia
- Digestive issues such as IBS
- Mood issues or brain fog
- A general health checkup to look at vitamin levels and other useful markers
- Pain, stiffness and inflammation or kidney stones (can be oxalates)
- Athletes or people wanting to optimise their health
- Those with a chronic health issue who have had other tests come back normal
The test provides information about:
Gut Health – microbial imbalances, such as yeast or bacterial overgrowth
Only an organic acid test to distinguish between beneficial and harmful bacteria, different types of Clostridia, and yeast (Candida).
Energy Production
The test includes markers for each stage of the Krebs cycle, which is used to create ATP or energy in our cells. Shows exactly how your mitochondria (powerhouses of your cells) may not be producing enough ATP. Precise supplementation is then possible.
Vitamins and Antioxidants
Vitamin status. Markers include Vitamins B12, B6, B5, B2, and C, Coenzyme Q10, N-Acetylcysteine and Biotin.
Neurotransmitter Balance Affecting Mood
Markers for dopamine epinephrine, and quinolinic acid.
- Fatty acid metabolism
Detoxification
- Detoxification, anti-oxidants (glutathione) levels and Oxidative
- Mould Exposure
- Oxalates
- Inborn errors of metabolism
Based on the results, a targeted diet and supplement plan can be created to correct any microbial imbalance and restore healthy cellular metabolism.
The GPL-MycoTOX is a comprehensive mycotoxin test
Mould is a fungus, and it grows virtually everywhere on Earth. Lately, mould has become a hot topic because of increasing awareness about its potential health hazards. Mycotoxins are some of the most prevalent toxins in the environment. Mycotoxins are chemicals (metabolites) produced by fungi like mould, which can infest buildings, vehicles, and foodstuffs, they grow anywhere where it is warm and damp. A majority of mycotoxin exposures are through food ingestion or airborne exposure. In the European Union, 20% of all grains harvested are contaminated with mycotoxins. Unfortunately, mycotoxins are resistant to heat and many processing procedures.
Fungi can grow on almost any surface, especially if the environment is warm and wet. Inner wall materials of buildings, wallpaper, fibreglass insulation, ceiling tiles, and gypsum support are all good surfaces for fungi to colonize. These fungi then release mycotoxins into the environment causing symptoms of many different chronic diseases.
Diseases and symptoms linked to mycotoxin exposure include fever, pneumonia-like symptoms, heart disease, rheumatic disease, asthma, sinusitis, cancer, memory loss, vision loss, chronic fatigue, skin rashes, depression, ADHD, anxiety, and liver damage. With our new MycoTOX Profile, we can identify mycotoxin exposures and make recommendations for detoxification treatments that have been effective.
Common moulds that produce harmful mycotoxins include Aspergillus moulds (black mould), penicillium moulds, and Fusarium moulds.
MycoTOX screens for eleven different mycotoxins, from 40 species of mould, in one urine sample.
DUTCH Complete Test by Precision Analytical
The DUTCH test, offered by Precision Analytical, is a comprehensive hormone test that stands for Dried Urine Test for Comprehensive Hormones. This test involves collecting dried urine samples over a 24-hour period, which are then analyzed to assess various hormone levels and their metabolites.
The DUTCH test is useful for testing and assessing hormone levels and their metabolism in the body. It provides valuable information about:
1. Hormone Levels: The test measures levels of key hormones such as cortisol (stress hormone), estrogen, progesterone, testosterone, DHEA (dehydroepiandrosterone), and their metabolites. This helps in evaluating hormone balance and identifying any deficiencies or excesses.
2. Hormone Metabolism: The test assesses how hormones are broken down and metabolized by the body. This includes evaluating the pathways of estrogen metabolism, which is important for understanding the risk of hormone-related conditions such as estrogen dominance or breast cancer.
3. Adrenal Function: The DUTCH test provides insights into adrenal function by measuring cortisol levels throughout the day. This helps in assessing the body’s stress response and identifying issues like adrenal fatigue or dysfunction.
4. Hormone Imbalances: By analyzing hormone levels and their metabolites, the test can identify hormone imbalances that may contribute to symptoms such as fatigue, mood swings, weight gain, sleep disturbances, and reproductive issues.
Overall, the DUTCH test offers a comprehensive and detailed analysis of hormone status, metabolism, and adrenal function, providing valuable insights for personalized hormone therapy, optimizing health, and addressing hormonal imbalances. It is particularly beneficial for individuals with symptoms suggestive of hormone-related issues or those seeking a deeper understanding of their hormone health.
DUTCH Plus Test by Precision Analytical
The DUTCH Plus test, offered by Precision Analytical, is an advanced hormone test that builds upon the Dried Urine Test for Comprehensive Hormones (DUTCH) by including additional markers to provide a more comprehensive assessment of hormone metabolism and overall health.
The DUTCH Plus test is useful for testing and evaluating a wide range of hormone levels and metabolic pathways, offering detailed information about:
1. Comprehensive Hormone Analysis: Like the DUTCH test, the DUTCH Plus measures key hormones such as cortisol (stress hormone), estrogen, progesterone, testosterone, DHEA (dehydroepiandrosterone), and their metabolites. This helps in assessing hormone balance and identifying underlying hormonal issues.
2. Organic Acids and Vitamin Markers: The DUTCH Plus includes markers for organic acids, which provide insights into energy production, detoxification, and nutrient metabolism. It also measures vitamin B6, B12, and glutathione levels, important for overall health and vitality.
3. Neurotransmitter Metabolites: This test evaluates neurotransmitter metabolites such as dopamine and serotonin, which play crucial roles in mood regulation, cognition, and overall mental well-being.
4. Oxidative Stress Markers: The DUTCH Plus assesses oxidative stress by measuring markers like 8-OHdG, providing information about cellular damage and antioxidant status.
5. Additional Hormone Insights: In addition to standard hormone analysis, the DUTCH Plus offers insights into hormone detoxification pathways, methylation status, and potential genetic factors influencing hormone metabolism.
Overall, the DUTCH Plus test provides a comprehensive and integrated view of hormone balance, metabolism, nutrient status, and overall health. It is particularly valuable for individuals seeking a deeper understanding of their health, addressing complex health issues, optimizing wellness, and guiding personalized treatment approaches. The detailed information obtained from this test can guide targeted interventions to support hormone balance, optimize cellular function, and promote overall well-being.
Metabolomix+
The Metabolomix+ test by Genova Diagnostics is an advanced comprehensive urine test that evaluates various metabolic pathways and markers to assess overall health and identify underlying imbalances or dysfunctions.
The Metabolomix+ test is useful for testing and evaluating a wide range of metabolic processes and provides detailed information about:
1. Organic Acid Analysis: This test measures organic acids in urine, reflecting metabolic processes related to energy production, detoxification, nutrient metabolism, and neurotransmitter function. Abnormal levels of specific organic acids can indicate deficiencies, imbalances, or impaired metabolic pathways.
2. Amino Acid Analysis: The test assesses amino acid levels, which are essential for protein synthesis, neurotransmitter production, and other vital functions in the body. Imbalances in amino acids can impact various aspects of health, including muscle function, cognitive performance, and immune function.
3. Nutritional Markers: The Metabolomix+ test evaluates levels of vitamins, minerals, antioxidants, and coenzymes, providing insights into nutritional status and potential deficiencies that may contribute to health issues or metabolic dysfunctions.
4. Detoxification Capacity: It assesses detoxification pathways and measures markers related to phase I and phase II detoxification processes. Impaired detoxification can lead to toxin accumulation and contribute to various health problems.
5. Mitochondrial Function: The test includes markers of mitochondrial function, which are crucial for cellular energy production and overall metabolic health. Dysfunctional mitochondria can impact energy levels, metabolism, and overall vitality.
6. Oxidative Stress and Inflammation: The Metabolomix+ test evaluates markers of oxidative stress and inflammation, providing insights into cellular damage, antioxidant capacity, and inflammatory processes within the body.
Overall, the Metabolomix+ test offers a comprehensive analysis of metabolic pathways, nutrient status, detoxification capacity, and mitochondrial function. It is particularly valuable for individuals with chronic health issues, unexplained symptoms, or metabolic imbalances seeking a deeper understanding of their health and personalized treatment strategies. The detailed information obtained from this test can guide targeted interventions to optimize metabolic health, address nutritional deficiencies, and support overall wellness and vitality.
Book Blood Tests in Leicester
The NutrEval test by Genova Diagnostics
The NutrEval test by Genova Diagnostics is a comprehensive nutritional assessment that provides insights into individual nutrient deficiencies, imbalances, and metabolic dysfunctions. This test is designed to evaluate various aspects of nutritional status and metabolism to support personalised treatment and optimise overall health.
Here’s what the NutrEval test is useful for testing and provides information about:
1. Comprehensive Nutrient Analysis:
The NutrEval test assesses levels of essential vitamins, minerals, amino acids, fatty acids, antioxidants, and other nutrients crucial for optimal health. It helps identify deficiencies, excesses, or imbalances that may contribute to various health conditions or symptoms.
2. Functional Markers:
In addition to measuring nutrient levels, the NutrEval test evaluates functional markers related to nutrient metabolism, including methylation, detoxification pathways, oxidative stress, mitochondrial function, and neurotransmitter metabolism. These functional assessments provide a holistic view of metabolic processes and identify underlying factors affecting health and well-being.
3. Digestive Health:
The test includes markers related to digestive health, such as markers for intestinal health, gut inflammation, absorption of nutrients, and microbial balance (gut microbiome). This helps in identifying digestive disorders, food sensitivities, or gut dysfunctions impacting nutrient absorption and overall health.
4. Toxin Exposure:
The NutrEval test measures levels of environmental toxins, heavy metals, and chemical exposures that may interfere with nutrient absorption, metabolism, and detoxification processes. This information is essential for identifying toxic exposures and their potential impact on health.
5. Comprehensive Report and Recommendations:
Based on the test results, the NutrEval report provides detailed insights and personalised recommendations for dietary modifications, nutritional supplements, lifestyle changes, and targeted interventions to address identified deficiencies or imbalances. This allows healthcare providers to develop tailored treatment plans to support optimal nutritional status and overall health.
Overall, the NutrEval test (Blood & Urine) is a valuable tool for assessing individual nutritional status, identifying underlying factors contributing to health issues, and guiding targeted interventions to optimise nutrient balance, support metabolic function, and promote overall well-being. It is particularly beneficial for individuals with chronic health conditions, unexplained symptoms, or those seeking a personalised approach to nutritional optimisation and disease prevention. The comprehensive nature of the NutrEval test provides a detailed assessment of multiple aspects of health and serves as a foundation for evidence-based treatment strategies aimed at improving overall health outcomes.
