Advanced Health Check in Leicester

Here is what is included with a Bone Health Check: Calcium, Vitamin D, Parathyroid Hormone (PTH)

These three markers help assess bone metabolism and calcium regulation:

• Calcium: Essential for bone strength, muscle function, and nerve signalling; imbalances can indicate bone or gland issues.
• Vitamin D: Aids calcium absorption; deficiency can lead to weak bones or osteoporosis.
• Parathyroid Hormone (PTH): Regulates calcium and phosphate levels; abnormal levels may signal parathyroid or kidney problems.

Together, they help diagnose conditions like osteoporosis, hyperparathyroidism, and vitamin D deficiency.

Here is what is included in a Diabetes Health check: Glucose, Glycated Haemoglobin (HbA1c), Insulin, C-Peptide.

These tests assess blood sugar control and insulin function:

• Glucose: Measures current blood sugar levels; high levels suggest diabetes or impaired glucose metabolism.
• Glycated Haemoglobin (HbA1c): Reflects average blood sugar over 2-3 months; key marker for diabetes diagnosis and management.
• Insulin: Measures insulin hormone levels; helps evaluate insulin production and resistance.
• C-Peptide: Indicates how much insulin the body produces, useful to distinguish between type 1 and type 2 diabetes.

Together, they provide a comprehensive picture of glucose metabolism and diabetes status.

An Electrocardiogram (ECG) Test records the electrical activity of your heart to detect any abnormalities. It’s a quick, painless test that helps assess your heart health and identify potential issues.

An electrocardiogram (ECG or EKG) records the heart’s electrical activity. It helps:

• Detect irregular heart rhythms (arrhythmias)
• Identify heart attacks or damage
• Assess heart size and function
• Monitor the effects of medications or devices

It’s a quick, non-invasive test crucial for diagnosing many heart conditions.

Here is what is included in a Full Blood count: Haemoglobin (Hb), Haematocrit (Hct), Mean Cell Haemoglobin (MCH), Mean Cell Haemoglobin Concentration (MCHC), Mean Cell Volume (MCV), Red Blood Cell Count (RBC), Basophil Count, Lymphocyte Count, Eosinophil Count, Monocyte Count, Neutrophil Count, White Blood Cell Count (WBC), Platelet Count (PLT), Red Cell Distribution Width (RDW), Mean Platelet Volume (MPV), Reticulocyte Count (Retics), Absolute Reticulocyte Count (Retics Absolute)

These 17 blood markers form a Complete Blood Count (CBC) with differential and reticulocyte count, providing detailed insights into blood health:

• Haemoglobin (Hb): Oxygen-carrying protein in red blood cells; low levels suggest anaemia.
• Haematocrit (Hct): Proportion of red cells in blood; indicates hydration and anaemia status.
• Mean Cell Haemoglobin (MCH): Average haemoglobin per red cell.
• Mean Cell Haemoglobin Concentration (MCHC): Concentration of haemoglobin in red cells.
• Mean Cell Volume (MCV): Average size of red blood cells; helps classify anaemia types.
• Red Blood Cell Count (RBC): Number of red cells; low in anaemia.
• Basophil Count: White cells involved in allergic responses.
• Lymphocyte Count: Key immune cells; changes indicate infections or immune disorders.
• Eosinophil Count: Elevated in allergies or parasitic infections.
• Monocyte Count: Phagocytic cells involved in inflammation.
• Neutrophil Count: Primary defenders against bacterial infections.
• White Blood Cell Count (WBC): Total immune cells; high or low counts indicate infection or disease.
• Platelet Count (PLT): Cells involved in blood clotting.
• Red Cell Distribution Width (RDW): Variation in red cell size; helps diagnose types of anaemia.
• Mean Platelet Volume (MPV): Average size of platelets; can indicate platelet production issues.
• Reticulocyte Count (Retics): Immature red blood cells; indicate bone marrow activity.
• Absolute Reticulocyte Count (Retics Absolute): Total number of reticulocytes; important in anaemia evaluation.

This panel helps diagnose anaemia, infections, immune conditions, clotting disorders, and bone marrow function.

Here is what is included in a Heart Health check: Total Cholesterol, Low-Density Lipoprotein Cholesterol (LDL), High-Density Lipoprotein Cholesterol (HDL), Total Cholesterol to HDL Ratio, Cholesterol Ratio, Triglycerides, Apolipoprotein A-I (Apo A-I), Apolipoprotein B (Apo B), Apolipoprotein B to A-I Ratio (Apo B/A-I Ratio), Lipoprotein (a) [Lp(a)], High-Sensitivity C-Reactive Protein (hs-CRP).

These markers provide a comprehensive cardiovascular risk profile, combining lipid levels, protein markers, and inflammation indicators:

• Total Cholesterol: Measures all cholesterol types in the blood.
• LDL (Low-Density Lipoprotein): “Bad” cholesterol; contributes to arterial plaque.
• HDL (High-Density Lipoprotein): “Good” cholesterol; helps clear LDL from blood.
• Total Cholesterol to HDL Ratio / Cholesterol Ratio: Evaluates heart disease risk; lower ratios are better.
• Triglycerides: Blood fats; high levels are linked to heart disease and metabolic disorders.
• Apolipoprotein A-I (Apo A-I): Main protein in HDL; protective against heart disease.
• Apolipoprotein B (Apo B): Found in LDL and other atherogenic particles; a strong indicator of cardiovascular risk.
• Apo B/A-I Ratio: Reflects the balance of “bad” vs. “good” lipoproteins; higher ratios suggest higher risk.
• Lipoprotein (a) [Lp(a)]: Genetic risk factor for cardiovascular disease; not modified by lifestyle.
• High-Sensitivity C-Reactive Protein (hs-CRP): Marker of low-grade inflammation; elevated levels predict higher heart disease risk.

This advanced lipid and inflammation panel gives a detailed view of heart disease risk beyond standard cholesterol tests.

An InBody Composition Scan to accurately measure your body fat, muscle mass, and overall health. This quick, non-invasive test provides detailed insights to help you achieve your fitness goals.

An InBody Body Composition Scan measures detailed body composition using bioelectrical impedance. It provides data on:

• Body fat percentage
• Muscle mass (skeletal and total)
• Body water content
• Basal metabolic rate (BMR)
• Visceral fat level

This scan helps track fitness, nutrition, and health progress by showing muscle-to-fat ratios and hydration status. It’s quick, non-invasive, and widely used in health and fitness settings.

We will also check your C-Reactive Protein (CRP) in the Infection & Inflammation check.

C-Reactive Protein (CRP):
CRP is a marker of inflammation in the body. It is produced by the liver in response to infection, injury, or chronic inflammatory conditions.

• Elevated CRP may indicate infection, autoimmune disease (like rheumatoid arthritis), or cardiovascular risk.
• Normal/low CRP suggests minimal inflammation.
• It helps monitor disease activity and response to treatment.

Serum Iron, Transferrin, Ferritin, Total Iron Binding Capacity (TIBC), Transferrin Saturation (TS%).

These tests evaluate iron status and metabolism:

• Serum Iron: Measures the amount of circulating iron in the blood.
• Transferrin: The main protein that transports iron; levels rise when iron is low.
• Ferritin: Reflects iron stores in the body; low levels indicate iron deficiency, high levels can suggest inflammation or overload.
• Total Iron Binding Capacity (TIBC): Indicates the blood’s capacity to bind iron with transferrin; elevated in iron deficiency.
• Transferrin Saturation (TS%): Percentage of transferrin saturated with iron; low saturation suggests deficiency, high saturation may indicate overload.

Together, these tests diagnose iron deficiency, iron overload, and anaemia causes.

Here is what we include in the Kidney Health Check: Creatinine, Estimated Glomerular Filtration Rate (eGFR), Chloride, Potassium, Phosphate, Sodium, Urea, Magnesium, Uric Acid, Cystatin C, Total Protein.

These tests assess kidney function, electrolyte balance, and overall metabolic health:

• Creatinine: Waste product filtered by the kidneys; elevated levels may indicate impaired kidney function.
• eGFR (Estimated Glomerular Filtration Rate): Measures how well the kidneys filter blood; a key indicator of kidney function.
• Chloride: Helps regulate fluid and acid-base balance.
• Potassium: Essential for heart and muscle function; abnormal levels can be dangerous.
• Phosphate: Works with calcium in bone formation; levels are affected by kidney function.
• Sodium: Regulates fluid balance, blood pressure, and nerve/muscle function.
• Urea: Waste from protein metabolism; elevated levels may suggest kidney dysfunction or dehydration.
• Magnesium: Important for muscle, nerve, and enzyme function; imbalances can affect heart rhythm and neuromuscular health.
• Uric Acid: High levels may indicate gout or kidney issues.
• Cystatin C: A Sensitive marker of kidney function, often more accurate than creatinine in some cases.
• Total Protein: Measures albumin and globulins; low or high levels may indicate kidney, liver, or nutritional issues.

Together, these markers give a thorough evaluation of kidney health and electrolyte status.

Here is what we will check for with the Liver Health check: Alkaline Phosphatase (ALP), Alanine Aminotransferase / Glutamate Pyruvate Transaminase (ALT/GPT), Aspartate Aminotransferase / Glutamate Oxaloacetate Transaminase (AST/GOT), Gamma-Glutamyl Transferase (Gamma GT or GGT), Total Bilirubin, Albumin, Globulin.

These seven tests evaluate liver function and health:

• Alkaline Phosphatase (ALP): Elevated in liver disease, bile duct obstruction, or bone disorders.
• Alanine Aminotransferase (ALT/GPT): Enzyme released with liver cell damage; high levels indicate liver injury.
• Aspartate Aminotransferase (AST/GOT): Found in liver and muscle; elevated in liver damage or muscle injury.
• Gamma-Glutamyl Transferase (GGT): Sensitive indicator of liver and bile duct problems; often elevated with alcohol use.
• Total Bilirubin: Byproduct of red blood cell breakdown; high levels cause jaundice and indicate liver or bile duct issues.
• Albumin: Main protein made by the liver; low levels suggest impaired liver function or malnutrition.
• Globulin: A Group of proteins including antibodies; changes can reflect immune response or liver disease.

Together, these tests provide a comprehensive picture of liver function, injury, and related disorders.

Here is what is included in a Metabolic Syndrome check: Leptin.

Leptin is a hormone produced by fat cells that helps regulate appetite and energy balance:

• High leptin levels are often seen in obesity and may indicate leptin resistance, where the brain no longer responds properly to the hormone’s appetite-suppressing effects.
• Low leptin levels can be associated with starvation, extreme weight loss, or certain hormonal conditions.

Leptin testing can help evaluate metabolic health, obesity-related disorders, and rare causes of weight gain or loss.

Creatine Kinase.

Creatine Kinase (CK) is an enzyme found mainly in the heart, brain, and skeletal muscles. It plays a key role in energy production for muscle contractions.

• Elevated CK levels can indicate muscle damage from injury, exercise, inflammation (myositis), or heart conditions like a heart attack.
• Normal levels suggest no significant muscle or heart injury.

CK testing helps diagnose muscle diseases, monitor muscle damage, and assess heart attack severity.

Folate (Vitamin B9), Vitamin B12 (B12).

Folate (Vitamin B9) and Vitamin B12 (Cobalamin) are essential B vitamins involved in: Red blood cell formation, DNA synthesis, and nervous system function.

• Folate (Vitamin B9): Low levels can cause megaloblastic anaemia, fatigue, and, in pregnancy, increased risk of neural tube defects. Found in leafy greens, legumes, and fortified foods.
• Vitamin B12: Deficiency may lead to anaemia, nerve damage, memory issues, and fatigue. Common in vegans or those with absorption issues (e.g. pernicious anaemia).

Testing helps diagnose the causes of anaemia and neurological symptoms.

A Spirometry Test measures your lung function by assessing how much air you can inhale and exhale. This simple, non-invasive test helps diagnose and monitor respiratory conditions like asthma and COPD.

Spirometry is a common lung function test that measures how well you breathe. It assesses:

• Lung volume (how much air you can inhale and exhale)
• Airflow speed (how quickly you can exhale)
• Forced Vital Capacity (FVC) – total air exhaled forcefully

Forced Expiratory Volume in 1 second (FEV₁) – air exhaled in the first second

It helps diagnose and monitor conditions like asthma, COPD, and other respiratory disorders. The test is quick, non-invasive, and typically involves blowing into a mouthpiece connected to a machine.

Here is what is included in a Thyroid Health check: Free Triiodothyronine (FT3), Free Thyroxine (FT4), Thyroid Stimulating Hormone (TSH), Thyroglobulin Antibody (TgAb), Thyroid Peroxidase Antibodies (TPOAb).

These tests assess thyroid function and help diagnose thyroid disorders:

• Free Triiodothyronine (FT3): Active thyroid hormone; regulates metabolism. Abnormal levels may indicate hyper- or hypothyroidism.
• Free Thyroxine (FT4): Main hormone produced by the thyroid; helps control metabolism and energy.
• Thyroid Stimulating Hormone (TSH): Produced by the pituitary; stimulates the thyroid. High TSH often means underactive thyroid (hypothyroidism); low TSH suggests overactive thyroid (hyperthyroidism).
• Thyroglobulin Antibody (TgAb): Autoantibody that may indicate autoimmune thyroid disease like Hashimoto’s or Graves’ disease.
• Thyroid Peroxidase Antibodies (TPOAb): Often elevated in autoimmune thyroid disorders; used to confirm diagnosis.

Together, these tests provide a full picture of thyroid health, function, and potential autoimmune causes.

Here is what is included in a Tumour Markers check: Cancer Antigen 125 (CA125) [female], Cancer Antigen 15-3 (CA15-3) [female], Prostate-Specific Antigen (PSA) – Free [male], Prostate-Specific Antigen (PSA) – Total [male]

These markers are tumour markers used to monitor or help detect specific cancers:

• Cancer Antigen 125 (CA125) [female]: Mainly used to monitor ovarian cancer and sometimes other gynaecological cancers; levels can also rise with benign conditions.
• Cancer Antigen 15-3 (CA15-3) [female]: Used to monitor breast cancer progression or recurrence.
• Prostate-Specific Antigen (PSA) – Free [male]: Measures the unbound form of PSA; helps differentiate prostate cancer from benign prostate conditions.
• Prostate-Specific Antigen (PSA) – Total [male]: Overall PSA level; elevated levels may indicate prostate cancer, benign prostatic hyperplasia, or inflammation.

These tests assist in cancer diagnosis, monitoring treatment response, and detecting recurrence.

Here is what is included with a Urinalysis: Urine pH, Urine Protein, Urine Glucose, Ketones, White Blood Cells (WBCs), Red Blood Cells (RBCs), Casts, Urobilinogen, Nitrite, Bacterial Count, Culture and Sensitivities

Urinalysis to detect various health conditions:

• Urine pH: Indicates acidity; abnormal values can suggest infection or metabolic issues.
• Urine Protein: Presence may indicate kidney damage or disease.
• Urine Glucose: Found in diabetes or high blood sugar.
• Ketones: Appear in fat breakdown, seen in diabetes or fasting.
• White Blood Cells (WBCs): Sign of infection or inflammation.
• Red Blood Cells (RBCs): May indicate bleeding or injury in urinary tract.
• Casts: Kidney-originated particles; certain types suggest kidney disease.
• Urobilinogen: Elevated levels may indicate liver problems or hemolysis.
• Nitrite: Indicates bacterial infection (some bacteria convert nitrate to nitrite).
• Bacterial Count: Measures the quantity; helps diagnose infections.
• Culture and Sensitivities: Identifies bacteria and guides antibiotic treatment.

Together, these tests help diagnose infections, kidney issues, diabetes, and liver problems.