ISAC Molecular Allergy Testing in Leicester

ISAC Molecular Allergy Testing in Leicester

A Highly Detailed Molecular Allergy Panel for Complex Allergy Cases

The ImmunoCAP ISAC test is an advanced molecular allergy blood test at The Health Suite Leicester that analyses over 100 allergen components using microarray technology. It is designed for patients with complicated allergy presentations, multiple suspected triggers, or unusual reactions where standard testing may not provide enough clarity.

What the ISAC Test Includes

  • Blood sampling at The Health Suite, Leicester
  • Analysis of over 100 molecular allergen components
  • Identification of IgE sensitisation at the molecular level
  • Detection of cross-reactive carbohydrate determinants (CCDs)
  • A detailed laboratory report sent to your clinician

No follow-up appointment is included with this test. If interpretation support is required, a consultation can be booked separately.

When ISAC Testing May Be Helpful

ISAC is particularly useful when:

  • Multiple allergies or unclear reactions are suspected
  • Symptoms do not match results from skin prick tests
  • ALEX² testing is not required or has already been performed
  • There is suspected cross-reactivity (e.g., birch pollen and fruits)
  • A child has eczema or asthma requiring deeper allergen understanding
  • There is a history of anaphylaxis with unclear triggers
  • Adults or teenagers have difficult-to-explain reactions

ISAC can be used for both adults and children.

How ISAC Complements Skin Prick Testing and ALEX²

Skin Prick Testing (SPT):

  • First-line for most children
  • Immediate results
  • Ideal for common food and environmental allergens

ALEX²:

  • Broadest allergen panel (up to 300 allergens)
  • Combine extracts + components

ISAC:

  • Focuses on molecular component analysis (over 100 components)
  • Provides precision when specific proteins need to be identified
  • Useful in complex, multi-sensitised patients

Each test has a different purpose. ISAC is not a “replacement” test; it is a refinement tool for complex cases.

What ISAC Does NOT Diagnose

  • Food intolerances
  • Non-IgE-mediated digestive symptoms
  • Lactose intolerance
  • Coeliac disease
  • Delayed reactions independent of IgE

A clinician will advise if additional testing is needed.

This page describes the ISAC test only. A clinical consultation is NOT included. If booking directly for a child who has not been assessed at The Health Suite, a paediatric allergy consultation is required before the test can be approved. ISAC complements our existing allergy services, including skin prick testing and ALEX² testing, offering additional insight when required.

Why choose The Health Suite for ISAC Molecular Allergy Testing?

Precision in Complex Cases

The ISAC test analyses over 100 allergen components at the molecular level, providing detailed insights into complex or multi-allergen sensitivities that standard testing may miss.

Expert Clinical Support

Our specialists ensure the test is clinically appropriate, interpret results accurately, and help families understand cross-reactivity patterns and risk-associated allergens for safe, informed management.

Complementary Allergy Services

ISAC is integrated with our full allergy service, including skin prick testing and ALEX², allowing a complete, personalised assessment for children and adults with multiple or unclear allergic reactions.

Make an Appointment

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To book or enquire, please use the form below. Alternatively, you can call us to book your appointment.

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0116 241 0010

ISAC Molecular Allergy Testing at The Health Suite Leicester?

We recognise that choosing a treatment can be difficult. So if you have a question, feel free to contact us on the form and one of our treatment co-ordinators will be happy to help. We aim to reply to all queries within 24 hours (Monday- Friday).

How the ISAC Test Works

1. Pre-Assessment Requirement

If a child has not been seen previously at The Health Suite for allergy concerns, an initial paediatric allergy consultation is required before ISAC can be booked. This ensures:

  • The test is appropriate
  • The child’s symptoms warrant molecular testing
  • Skin prick testing or ALEX² might be more suitable

2. Blood Sample Collection

A simple blood test is performed by our clinical team.

3. Laboratory Microarray Analysis

ISAC uses molecular microarray technology to measure specific IgE to allergen components, offering detailed insights into:

  • Food allergens
  • Pollens
  • Pets
  • Dust mites
  • Moulds
  • Venoms
  • Cross-reactive Proteins

4. Comprehensive Report

The clinician receives a full molecular-level profile, including:

  • IgE binding to individual allergen proteins
  • Identification of cross-reactivity patterns
  • Risk-associated components
  • CCD markers

5. Optional Interpretation Consultation

An optional review appointment can be arranged if families wish to discuss results and develop a management plan.

ISAC Molecular Allergy Testing in Leicester

Treatment options and pricing

Browse and click below to book any of our available service.

£500 including Phlebotomy

ISAC Molecular Allergy Test

Advanced ISAC blood test for children & adults. Detects over 100 allergen components for precise allergy insights and personalised management plans.

Included in the ISAC Molecular Allergy Test

– Includes phlebotomy and full laboratory analysis
– No consultation included

A clinician review is required before booking directly for any child.

FAQ

Common Q&A about ISAC Molecular Allergy Testing

Our FAQ section is designed to address common questions you may have, from how our treatments work to what you can expect during and after your session.

Our team is always available to provide additional support if you need more personalised guidance, ensuring that you feel informed and confident every step of the way.

No. ISAC complements existing tests by offering deep molecular detail when needed.

Yes, for children who have not previously been reviewed at The Health Suite. Adults may require a clinical review depending on the case.

No. Interpretation can be booked separately.

ISAC indicates which proteins are associated with higher-risk reactions, but it cannot predict exact severity.

Yes. ISAC is particularly effective at mapping cross-reactivity between allergens.

No. Antihistamines do not influence blood-based IgE testing.

Some clinicians prefer ISAC for its focused molecular components, especially when a very specific profile is needed.

Yes. It includes pollens, pets, dust mites, moulds, and more.

Yes, as long as a clinician confirms it is appropriate.

Symptom checker

If you are experiencing any of these symptoms, please book an appointment with us. Symptoms can vary from person to person and from condition to condition.A proper diagnosis can only be made through a thorough medical examination.

Our clinicians will carry out a full assessment to ensure an accurate diagnosis and appropriate care.

ISAC is ideal when symptoms do not match standard skin prick or ALEX² tests, helping identify hidden allergen triggers at the molecular level.

Complex or persistent skin reactions can be clarified by molecular IgE profiling with ISAC for precise allergen identification.

ISAC detects IgE sensitisation to foods, pollens, pets, dust, moulds, and venoms to pinpoint elusive allergy triggers.

ISAC maps molecular-level patterns to detect cross-reactive allergens, such as birch pollen with certain fruits, for tailored management.

ISAC helps identify high-risk allergen proteins, providing detailed insights to guide avoidance and safety strategies.

ISAC complements skin prick and ALEX² testing, offering focused molecular analysis for complex, multi-sensitised patients.

What we treat

At The Health Suite Leicester, our private medical clinic offers expert care whenever you need it. Our team of experienced GPs and healthcare professionals provide personalised diagnosis and treatment for a wide range of medical conditions, ensuring high-quality, professional care in a comfortable setting.

Click below to view useful info on a few of the common conditions we treat:

Detailed profiling for patients with multiple triggers or unclear reactions.

Identification of molecular-level sensitisation to common and rare foods.

Detection of pollens, pets, dust mites, moulds, and venom sensitivities.

Recognises molecular links between allergens to inform avoidance and management plans.

Provides insight for conditions requiring detailed IgE analysis.

Our clinicians manage a broad spectrum of conditions, and individual assessment allows us to tailor care beyond the examples listed. We encourage you to book a consultation to discuss your symptoms and appropriate treatment options.

Meet our ISAC Molecular Allergy Testing Clinicians

Meet our dedicated team at The Health Suite Leicester, where skilled professionals are committed to providing exceptional care tailored to your medical and wellness needs.

Dr Shilpee Sinha

Dr Shilpee Sinha

Consultant Paediatrician with a specialist interest in Paediatric Allergy